At PhD Trials®, we routinely perform In vivo Safety studies (HRIPT, Patch Tests, ROATS, Open Tests) to evaluate cosmetic products and raw materials.
We have an extensive database of volunteers with several typologies (sensitive/reactive, atopic, acne prone and normal skin), and an experienced team to perform in vivo safety studies.
Our main safety studies are:
Human Repeated Insult Patch Test (HRIPT)
Single or Repeated Patch Test
Repeated Open Application Tests (ROAT)
In use studies for tolerance evaluation
In vivo efficacy: General Methods
PhD Trials® is the laboratory to substantiate your claim. We have all the general methods to study the interaction of your product with the human skin.
We are worldwide recognized for having developed some of the most used techniques to substantiate the efficacy of cosmetic products:
Trans Epidermal Water Loss (TEWL)
In vivo efficacy: Advanced Methods
From Confocal microscopy, AEVA-HE, skin microcirculation and professional imaging studios (with high resolution cameras and VISIA-CR), at PhD Trials we can show how good your product is. At PhD Trials®, we design specific studies to your claims. We are recognized for our very complete reports in all studies. Our advanced clinical photography laboratories are fully equipped to perform digital and 3D photos (AEVA, Vectra and Primos systems) from all parts of the body in high detail and resolution to help the visualization of the effects of your product.
Some of our advanced tests are:
Skin topography evaluation
Skin temperature & structure
Skin 3D topography
Assessment of cutaneous barrier
Hair Physiology Evaluation
Hair products are among the most used cosmetic products.
Our new Hair Evaluation Lab was developed to study the human hair in several conditions (in vivo and ex vivo).
In vivo studies – Clinical evaluation, Visioscan, Image analysis
Ex vivo evaluation – Hair tresses with specific chamber, Hair tresses with combing machine, Hair tresses with force system, Image analysis, UV protection, Color protection of hair against repetitive washing, Wet and Dry combing, Thermal protection, Anti-frizz effect, Volume effect, Shining effect, Smoothness effect
Hair evaluation – TrichoScan HD for Hair grow, density and anagen/telogen rate
The European Cosmetic Regulation presented challenges that can only be solved with experienced consultants.
At PhD Trials® we perform safety assessments of finished cosmetic products, new formulation development and improvement according with the European regulations.
In vitro testing for claim substantiation and product development, (e.g. Het-CAM, BCOP).